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The main research topics in our group are the design, synthesis and application of polymeric materials in chemical biology and biomedical applications. We are hoping to utilize polymers as a platform for complicated structures through rational design and controlled chemical synthesis. By introducing functional groups and moieties that have known functions and biological activities, such as charges, hydrogen bonding donors and acceptors, protein/DNA/RNA ligands and binders, we aim to further enhance the activity and efficacy of these known moieties on the polymers by effecting special structural features and synergistic effects, visualizable in either cellular or animal studies. Biological system is extremely complicated – and our concept is that a complicated problem needs a complicated solution. Indeed, polymeric material is a must for constructing a complicated solution.

Our group is located in the Institute of Chemical Biology and Nanomedicine (ICBN) on Hunan University main campus, and is a part of the State Key Laboratory of Chem/Biosensing and Chemometrics, and a part of the Provincial Key Laboratory of Biomacromolecular Chemical Biology. We have access to various advanced scientific instruments in the group and the institute. We also have sufficient funding and excellent office/laboratory environment for all of our students. The Bai group sincerely welcomes all graduate students and undergraduates who have interests in our research topics. If you need more information on our ongoing projects, please go to the Research page.